Popular diabetes and weight-loss drug associated with lower opioid overdose risk

Case Western Reserve University School of Medicine identifies a potential new approach to address the opioid overdose epidemic—which has devastated families and communities nationally. Semaglutide was found to lower opioid overdoses in people with opioid-use disorder (OUD) and type 2 diabetes (T2D).

Fentanyl May Increase or Decrease Oxygen Levels Depending on Dosage

Article title: Oxygen fluctuations in the brain and periphery induced by intravenous fentanyl: effects of dose and drug experience Authors: Shinbe Choi, Michael R. Noya, Eugene A. Kiyatkin From the authors: “We report that fentanyl’s effects are highly dose-dependent, drawing…

Could monoclonal antibodies replace opioids for chronic pain?

During the pandemic, physicians used infusions of monoclonal antibodies to help patients fight off COVID-19 infections. Now, in response to the U.S. opioid crisis, researchers at UC Davis are trying to create monoclonal antibodies that can help fight chronic pain. The research is funded with a $1.5 million grant from the National Institutes of Health’s HEAL Initiative, an aggressive effort to speed scientific solutions to stem the national’s opioid crisis.

Sanford Burnham Prebys researchers awarded $6.4M to advance treatment for substance use disorders

Sanford Burnham Prebys Professor Nicholas Cosford, Ph.D., has been awarded $6.4M from the National Institute on Drug Abuse (NIDA) to test new potential drugs to treat opioid and methamphetamine use disorders. The three-year project will be completed with partners from Wake Forest University School of Medicine and Camino Pharma, LLC.

Patients’ Access to Opioid Treatment Cumbersome

The “secret shopper” study used trained actors attempting to get into treatment with an addiction provider in 10 U.S. states. The results, with more than 10,000 unique patients, revealed numerous challenges in scheduling a first-time appointment to receive medications for opioid use disorder, including finding a provider who takes insurance rather than cash.

Rutgers Dean Available to Speak about Rise of Drug Use and Abuse as a Result of the Mental Health Fallout from the COVID-19 Pandemic

The COVID-19 pandemic has led to unprecedented levels of unemployment, the need to quickly adapt to new living and working conditions, and uncertainties about our own health and future, leading individuals to experience anxiety, depression, and other mental health conditions…

Other treatments can reduce need for addictive pain medication

Hardly a day goes by without the public being warned about the dangers of opioids. But still, according to the National Institute on Drug Abuse, more than 130 people die every day of opioid overdose and the problem is getting worse. A Houston Methodist pain specialist says new advancements in pain management are giving patients options.