New AGA guideline finds that evidence to support use of probiotics to treat digestive diseases is greatly lacking, identifying only three clinical scenarios where probiotics may benefit patients
Tag: Gastroenterology
Serious complication of Crohn’s disease may be preventable in young people
Children and young adults with the inflammatory bowel disease may be less likely to develop perianal fistulas if they receive steroid-sparing therapies.
AGA does not recommend the use of probiotics for most digestive conditions
New AGA guideline finds that evidence to support use of probiotics to treat digestive diseases is greatly lacking, identifying only three clinical scenarios where probiotics may benefit patients
With $16.5 million in NIH funding, MUSC opens two new digestive disease research centers
The recent openings of two centers have put the Medical University of South Carolina on the map as a leading institution for digestive and liver disease research.
New clues on how lipid emulsions prevent liver disease in preterm babies
Infants born prematurely may require parenteral or intravenous nutrition to provide the necessary nourishment, as their digestive system is immature and cannot digest nutrients. However, prolonged parenteral nutrition is associated with complications, including cholestasis, or lack of bile flow from…
New clues on how lipid emulsions prevent liver disease in preterm babies
Infants born prematurely may require parenteral or intravenous nutrition to provide the necessary nourishment, as their digestive system is immature and cannot digest nutrients. However, prolonged parenteral nutrition is associated with complications, including cholestasis, or lack of bile flow from…
Gut research delves deeper into obesity problems
By delving deeper into metabolism problems, the research team has found that the nutrient sensing capacity of Enterochromaffin (EC) cells – which line the gastrointestinal tract and are the source of almost all serotonin in the body – have changed…
New gut-brain link: How gut mucus could help treat brain disorders
Changes in gut mucus could be contributing to bacterial imbalance and exacerbating core symptoms of brain disorders like autism, Parkinson’s disease, Alzheimer’s and Multiple Sclerosis
An imbalance of electrons in the liver may be a common risk factor for disease
BOSTON–Researchers at Massachusetts General Hospital have uncovered an unexpected connection between an imbalance of electrons in liver cells and many metabolic problems that increase the risk for conditions such as cardiovascular disease and fatty liver disease. Their findings, published in…
An imbalance of electrons in the liver may be a common risk factor for disease
BOSTON–Researchers at Massachusetts General Hospital have uncovered an unexpected connection between an imbalance of electrons in liver cells and many metabolic problems that increase the risk for conditions such as cardiovascular disease and fatty liver disease. Their findings, published in…
New report discusses coffee’s effect on digestion and digestive disorders
Research suggests that drinking coffee may help to reduce the risk of certain digestive disorders, including gallstone disease and pancreatitis, and benefit some elements of the digestive process, such as gut motility.
Gene inactivation of PTEN drives cancer predisposition
Study co-led by Cleveland Clinic published in New England Journal of Medicine
Four of ten adults worldwide have functional gastrointestinal disorders
For every ten adults in the world, four suffer from functional gastrointestinal disorders of varying severity. This is shown by a study of more than 73,000 people in 33 countries. University of Gothenburg scientists are among those now presenting these…
The AGA Research Foundation provides over $2 million in funding to promising researchers
The AGA Research Foundation funded 17 awards in the 2020 awards cycle
Gene inactivation of PTEN drives cancer predisposition
Study co-led by Cleveland Clinic published in New England Journal of Medicine
Four of ten adults worldwide have functional gastrointestinal disorders
For every ten adults in the world, four suffer from functional gastrointestinal disorders of varying severity. This is shown by a study of more than 73,000 people in 33 countries. University of Gothenburg scientists are among those now presenting these…
Altered sense of taste present in half of COVID-19 cases
Analysis could provide another clue for diagnosing the illness
The AGA Research Foundation provides over $2 million in funding to promising researchers
The AGA Research Foundation funded 17 awards in the 2020 awards cycle
A single negative colonoscopy associated with long-lasting and significantly reduced cancer incidence
Below please find summaries of new articles that will be published in the next issue of Annals of Internal Medicine . The summaries are not intended to substitute for the full articles as a source of information. This information is…
Are Gastrointestinal Symptoms Specific for COVID-19 Infection? A Prospective Case-Control Study from the United States
“To our knowledge, this is the first prospective case-control study of GI symptoms in COVID-19 patients. We found a high prevalence of GI symptoms (74%) in COVID-19 patients, with the most common GI symptoms being anorexia (53%) and diarrhea (50%). However,…
Weight loss surgery may alter gene expression in fat tissue
Altered gene expression in fat tissue may help explain why individuals who have regained weight after weight loss surgery still experience benefits such as metabolic improvements and a reduced risk of type 2 diabetes. The findings come from a study…
Weight loss surgery may alter gene expression in fat tissue
Altered gene expression in fat tissue may help explain why individuals who have regained weight after weight loss surgery still experience benefits such as metabolic improvements and a reduced risk of type 2 diabetes. The findings come from a study…
Examining melanoma risk in patients treated with biologics for common inflammatory diseases
What The Study Did: This study combined the results of seven studies and compared the risk of melanoma among 34,000 patients treated with biologics and 135,000 patients treated with conventional systemic therapy for rheumatoid arthritis, psoriasis or inflammatory bowel disease.…
Examining melanoma risk in patients treated with biologics for common inflammatory diseases
What The Study Did: This study combined the results of seven studies and compared the risk of melanoma among 34,000 patients treated with biologics and 135,000 patients treated with conventional systemic therapy for rheumatoid arthritis, psoriasis or inflammatory bowel disease.…
Navigating nonalcoholic fatty liver disease (NAFLD)
Special issue of Gastroenterology serves as clinician’s roadmap to the rapidly changing developments in NAFLD treatment
Researchers find potential drug treatment targets for alcohol-related liver disease
Alcohol-related liver disease (ALD) is a deadly condition affecting more than 150 million people worldwide with no treatment available besides transplant. But now, a team led by researchers from Massachusetts General Hospital (MGH) has uncovered key molecular step stones in…
Navigating nonalcoholic fatty liver disease (NAFLD)
Special issue of Gastroenterology serves as clinician’s roadmap to the rapidly changing developments in NAFLD treatment
Researchers find potential drug treatment targets for alcohol-related liver disease
Alcohol-related liver disease (ALD) is a deadly condition affecting more than 150 million people worldwide with no treatment available besides transplant. But now, a team led by researchers from Massachusetts General Hospital (MGH) has uncovered key molecular step stones in…
New study sheds light on IBD patients with COVID
In an upcoming study to be published in Gastroenterology, researchers at the Icahn School of Medicine at Mount Sinai and the University of North Carolina School of Medicine report on the clinical course of COVID-19 and risk factors for adverse outcomes in a large cohort of patients with IBD collected through an international registry.
New study sheds light on IBD patients with COVID
Researchers report findings from international registry
Notorious cancer protein mutations cooperate to proliferate disease
Understanding the genetic mutations and protein changes that take place in the progression of cancer is key to its treatment. Mutations in the gene TP53 and concomitant mutant p53 proteins in cancer cells have become notorious over the course of…
New study sheds light on IBD patients with COVID
Researchers report findings from international registry
Study traces brain-to-gut connections
PITTSBURGH, May 18, 2020 – Neuroscientists at the University of Pittsburgh Brain Institute have traced neural pathways that connect the brain to the stomach, providing a biological mechanism to explain how stress can foster ulcer development. The findings, published this…
Study traces brain-to-gut connections
PITTSBURGH, May 18, 2020 – Neuroscientists at the University of Pittsburgh Brain Institute have traced neural pathways that connect the brain to the stomach, providing a biological mechanism to explain how stress can foster ulcer development. The findings, published this…
Notorious cancer protein mutations cooperate to proliferate disease
Understanding the genetic mutations and protein changes that take place in the progression of cancer is key to its treatment. Mutations in the gene TP53 and concomitant mutant p53 proteins in cancer cells have become notorious over the course of…
Gut ecology
Researchers use old equations coupled with new methods to help decode the massively complex gut microbiome
Gut ecology
Researchers use old equations coupled with new methods to help decode the massively complex gut microbiome
Coronavirus infection in children — it may not start with a cough
Children suffering from sickness and diarrhea, coupled with a fever or history of exposure to coronavirus, should be suspected of being infected with COVID-19, recommends a new study published in Frontiers in Pediatrics.
Coronavirus infection in children — it may not start with a cough
Gastrointestinal symptoms, coupled with a fever or history of exposure to COVID-19, could indicate coronavirus infection in children
Coronavirus infection in children — it may not start with a cough
Gastrointestinal symptoms, coupled with a fever or history of exposure to COVID-19, could indicate coronavirus infection in children
Acupuncture may be safe and effective for easing indigestion symptoms
Embargoed news from Annals of Internal Medicine
Earlier gestational diabetes diagnosis, less weight gain
New Rochelle, NY, May 11, 2020–A new study has shown that initiating screening for gestational diabetes in high-risk women in the first trimester of pregnancy instead of the second trimester, allowing for treatment to start earlier, can help optimize gestational…
Acupuncture may be safe and effective for easing indigestion symptoms
Embargoed news from Annals of Internal Medicine
Earlier gestational diabetes diagnosis, less weight gain
New Rochelle, NY, May 11, 2020–A new study has shown that initiating screening for gestational diabetes in high-risk women in the first trimester of pregnancy instead of the second trimester, allowing for treatment to start earlier, can help optimize gestational…
Fatty liver disease is underdiagnosed in the US
A condition involving excess fat buildup in the liver is grossly underdiagnosed in the United States, according to an analysis of Medicare claims data. The condition, called nonalcoholic fatty liver disease (NAFLD), is often associated with obesity and is not…
Cholesterol lowering drugs linked to improved gut bacteria composition in obese people
The human gut microbiota consists of trillions of bacteria, fungi and virus constituting an inner chemical factory producing a multitude of microbial compounds affecting immunity, neurobiology and metabolism of the human host. It has for long been known that imbalances…
Management of inflammatory bowel diseases: Clinical perspectives
Special issue of Clinical Gastroenterology and Hepatology highlights major advances in inflammatory bowel diseases (IBD) treatment
Researchers find certain foods common in diets of US adults with inflammatory bowel disease
ATLANTA–Foods, such as French fries, cheese, cookies, soda, and sports and energy drinks, are commonly found in the diets of United States adults with inflammatory bowel disease, according to a new study by researchers in the Institute for Biomedical Sciences…
Cholesterol lowering drugs linked to improved gut bacteria composition in obese people
The human gut microbiota consists of trillions of bacteria, fungi and virus constituting an inner chemical factory producing a multitude of microbial compounds affecting immunity, neurobiology and metabolism of the human host. It has for long been known that imbalances…
Fatty liver disease is underdiagnosed in the US
A condition involving excess fat buildup in the liver is grossly underdiagnosed in the United States, according to an analysis of Medicare claims data. The condition, called nonalcoholic fatty liver disease (NAFLD), is often associated with obesity and is not…