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UrduWith one IV injection, a gene therapy targeting cBIN1 can reverse the effects of heart failure and restore heart function in a large animal model. The therapy increases the amount of blood the heart can pump and dramatically improves survival.
Tag: Cardiac Function
3 Keys to Assessing Cardiac Function in Neonatal Shock
Neonatal shock is an acute and potentially life-threatening condition for babies. To treat it, physicians must determine whether systolic or diastolic dysfunction—or both—is causing a lack of oxygen to the baby’s organs.But that’s not always a simple task.
Second Heart Assist Announces an Impressive Successful Completion of a First-In-Human Case Study in Central America with its Whisper™ Device
Utah-based Second Heart Assist Inc., announced today the successful completion of the company’s first Central American case to evaluate the performance of its Whisper™ percutaneous mechanical circulatory device, designed to improve both cardiac function and renal perfusion in patients hospitalized with acute decompensated heart failure (ADHF). Second Heart Assist has already successfully performed FIH studies in Panama (South America) and other OUS countries for multiple indications.
Game-changing potential for drug testing and cardiovascular disease treatments – Tiny Heart Model Carries Massive Implications
A remarkable breakthrough, a collaborative team of researchers has unveiled a miniature human heart model that could potentially transform drug testing and cardiovascular research.
Dissolving cardiac device monitors, treats heart disease
Nearly 700,000 people in the United States die from heart disease every year, and one-third of those deaths result from complications in the first weeks or months following a traumatic heart-related event. To help prevent those deaths, researchers at Northwestern and George Washington (GW) universities have developed a new device to monitor and treat heart disease and dysfunction in the days, weeks or months following such events.
Sedentary time may significantly enlarge adolescents’ heart
In adolescents, sedentary time may increase heart size three times more than moderate-to-vigorous physical activity, a paper published in the Scandinavian Journal of Medicine & Science in Sports concludes.
Wireless pacemakers may be safe, effective for children with irregular heart rhythms
Wireless or leadless pacemakers, commonly implanted in adults, may be a safe and effective short-term option for children with slow heartbeats, according to new research published today in Circulation: Arrhythmia and Electrophysiology, a peer-reviewed journal of the American Heart Association.
Review calls for a refreshed look at clinical approach to heart muscle disorder
The heart’s main pumping chamber – the lower left ventricle – contains pieces of muscle called trabeculations that extend into it. Excessive trabeculation, often referred to as non-compacted myocardium, has been described at all ages, from fetus to adult.
National study suggests it’s time to rethink how we treat atrial fibrillation
A national study led by UBC researchers at the Centre for Cardiovascular Innovation is shedding light on how to more effectively treat atrial fibrillation (AF) – a common heart rhythm problem associated with increased risk of stroke and heart failure.
Flu causes cardiac complications by directly infecting the heart
Researchers have shown for the first time in mice that heart problems seen in some of the sickest flu patients are caused by direct influenza infection of cardiac cells.
Bioprinted 3D Cardiac Patches Could Reverse Scar Formation, Promote Myocardial Regeneration After Heart Attacks
Myocardial infarction, or heart attacks, play a large part in heart diseases and the necrosis of cardiac tissue. In APL Bioengineering, researchers take stock of stem cell-laden 3D-bioprinted cardiac patch technologies and their efficacy as a therapeutic and regenerative approach for ischemic cardiomyopathy in reversing scar formation and promoting myocardial regeneration. They explore types of candidate stem cells that possess cardiac regenerative potential and share updates on the challenging implementation of the state-of-the-art 3D-bioprinting approach.
Mount Sinai Cardiologist Awarded $2.9 Million NIH Grant to Advance Work with Stem Cells and Heart Repair after Heart Attack
Research may lead to identifying novel therapies for cardiac patients