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UrduScientists at Sanford Burnham Prebys have developed a clearer picture of how crucial machinery in the human cell’s recycling process for obsolete and misshapen proteins—known as proteasomes—are formed.
Tag: Age-related Diseases
Activating molecular target reverses multiple hallmarks of aging
Researchers at The University of Texas MD Anderson Cancer Center have demonstrated that therapeutically restoring ‘youthful’ levels of a specific subunit of the telomerase enzyme can significantly reduce the signs and symptoms of aging in preclinical models. If these findings are confirmed in clinical studies, there may be therapeutic implications for age-related diseases such as Alzheimer’s, Parkinson’s, heart disease and cancer.
With the help of naked mole rats, Xiao Tian seeks to expose and explain the epigenetic drivers of aging
Xiao Tian, Ph.D., who recently joined Sanford Burnham Prebys as an assistant professor in the Degenerative Diseases Program, focuses on epigenomic changes and deterioration that influence age-related diseases.
Reduced Expression of Dual Oxidase 1 Enzyme May Contribute to Age-related Emphysema
Article title: Downregulation of DUOX1 function contributes to aging-related impairment of innate airway injury responses and accelerated senile emphysema Authors: Caspar Schiffers, Lennart K.A. Lundblad, Milena Hristova, Aida Habibovic, Christopher M. Dustin, Nirav Daphtary, Minara Aliyeva, David J. Seward, Yvonne M.…
Using Blood to Combat Age-related Muscle Loss
Article title: The effect of young and old ex vivo human serum on cellular protein synthesis and growth in an in vitro model of ageing Authors: Sophie L. Allen, Ryan N. Marshall, Sophie J. Edwards, Janet M. Lord, Gareth G.…
Researchers Use Two-photon Microscopy, Optical Coherence Tomography to View Age-related Blood-brain Barrier Changes
Article title: Demonstration of age-related blood-brain barrier disruption and cerebromicrovascular rarefaction in mice by two-photon microscopy and optical coherence tomography Authors: Ádám Nyúl-Tóth, Stefano Tarantini, Jordan Delfavero, Feng Yan, Priya Balasubramanian, Andriy Yabluchanskiy, Chetan Ahire, Tamas Kiss, Tamas Csipo, Agnes…
Science Snapshots: COVID-19, power outages, Alzheimer’s disease, and optical antennas
March Science Snapshots from Berkeley Lab
Scientists Discover New Clue Behind Age-Related Diseases and Food Spoilage
Berkeley Lab scientists have made a surprising discovery that could help explain our risk for developing chronic diseases or cancers as we get older, and how our food decomposes over time.
More than Just a Carnival Trick: Researchers Can Guess Your Age Based on Your Microbes
UC San Diego and IBM researchers reveal a new understanding of how our microbiomes change as we age, setting the stage for future research on the role microbes play in accelerating or decelerating the aging process and influencing age-related diseases.