Tag: Morphine

A Common Pathway in the Brain That Enables Addictive Drugs to Hijack Natural Reward Processing Has Been Identified by Mount Sinai

sarah JonasResearch Results

Mount Sinai researchers, in collaboration with scientists at The Rockefeller University, have uncovered a mechanism in the brain that allows cocaine and morphine to take over natural reward processing systems.

How AI Can Help Design Drugs to Treat Opioid Addiction

sarah JonasResearch Results

ROCKVILLE, MD – Approximately three million Americans suffer from opioid use disorder, and every year more than 80,000 Americans die from overdoses. Opioid drugs, such as heroin, fentanyl, oxycodone and morphine, activate opioid receptors. Activating mu-opioid receptors leads to pain relief and euphoria, but also physical dependence and decreased breathing, the latter leading to death in the case of drug overdose.

A new way to control pain after knee replacement surgery

sarah JonasResearch Results

Houston Methodist researchers present clinical evidence supporting the safety and efficacy of injecting pain medication directly into the tibia during knee replacement surgery for better postoperative pain management. The study revealed patients receiving a mixture of morphine and vancomycin injected into the shin bone have less pain post-surgery than those who received the infusion without morphine during surgery.