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UrduRice, UTHealth, UH researchers detail architecture of the cytoskeleton in neurons
Tag: Molecular Biology
Runaway mitochondria cause telomere damage in cells
PITTSBURGH, Aug. 26, 2019 – Researchers at UPMC Hillman Cancer Center provide the first concrete evidence for the long-held belief that sick mitochondria pollute the cells they’re supposed to be supplying with power. The paper, published this week in the…
Scientists have found longevity biomarkers
An international group of scientists studied the effects of 17 different lifespan-extending interventions on gene activity in mice and discovered genetic biomarkers of longevity. The results of their study were published in the journal Cell Metabolism . Nowadays, dozens of…
Breath! Respiring microbes generate more energy
Researchers have now shed light on how bacteria and baker’s yeast generate and use their energy to g
Novel paradigm in drug development
Understanding resistance mechanisms to targeted protein degradation
Researcher works to understand how gonorrhea develops resistance to antibiotics
Steadily and relentlessly, the bacterium that causes gonorrhea has slipped past medicine’s defenses, acquiring resistance to once-reliable drugs, including penicillin, tetracycline, and ciprofloxacin. These former stalwarts are no longer used to treat the sexually transmitted disease. In 2010, after some…
K+ Channel Study Could Help Develop Drugs for Life-Threatening Conditions
TTUHSC’s Cuello has Research Published in PNAS
A novel technology for genome-editing a broad range of mutations in live organisms
Salk scientists develop a new gene-editing tool that could help treat many disorders caused by gene
Dartmouth receives $12.5 million grant to establish Center for Quantitative Biology
Dartmouth’s Geisel School of Medicine has been awarded a 5-year, $12.5 million grant from the National Institutes of Health (NIH) to establish a Center for Quantitative Biology (CQB) that will bring together and enhance initiatives in computational biology, bioinformatics, and…
Genetic redundancy aids competition among bacteria in symbiosis with squid
The molecular mechanism used by many bacteria to kill neighboring cells has redundancy built into its genetic makeup, which could allow for the mechanism to be expressed in different environments. Some strains of luminescent bacteria that compete to colonize the…
TGen team links gene to children with physical and intellectual disabilities
DDX6 among a growing list of genes identified by TGen’s Center for Rare Childhood Disorders
Immune cells drive gallstone formation
Sticky meshworks of DNA and proteins extruded by white blood cells called neutrophils act as the glue that binds together calcium and cholesterol crystals during gallstone formation, researchers in Germany report August 15 in the journal Immunity . Both genetic…
NIH awards $17.4 million to Cornell for CHESS subfacility
A single human cell contains thousands of proteins that perform a vast array of functions, from fighting off viruses to transcribing DNA. By understanding the structure of these proteins, researchers can interpret their functions and develop methods for turning them…
New drug targets early instigator of Alzheimer’s disease
Over a hundred years after they were first identified, two ominous signposts of Alzheimer’s disease (AD) remain central topics of research–both formed by sticky accumulations of protein in the brain. Amyloid beta solidifies into senile plaques, which congregate in the…
Findings shed new light on why Zika causes birth defects in some pregnancies
One thing is clear when it comes to Zika: pregnant women must do everything they can to avoid getting infected. If the virus gains entry to the mother’s cells, it can also infect the baby and cause severe birth defects,…
New proteomics technique gives insights into ubiquitin signalling
Australian researchers are among the first in the world to have access to a new approach to understand intricate changes that control how proteins function in our cells in health and disease. The new proteomics technique called ‘ubiquitin clipping’ allows…
Sticky proteins help plants know when — and where — to grow
New research uncovers a mechanism that keeps hormone auxin in its place
Adding MS Drug to Targeted Cancer Therapy May Improve Glioblastoma Outcomes
The multiple sclerosis drug teriflunomide, paired with targeted cancer therapy, markedly shrinks patient-derived glioblastomas grown in mice by reaching stem cells at the tumor’s root, according to a new UC San Diego School of Medicine study published in Science Translational Medicine.