Scientists have unveiled a revolutionary protospacer adjacent motif (PAM)-less genome editing system using CRISPR-SpRY, marking a major advancement in soybean breeding. This innovative method eliminates the traditional PAM sequence constraints, enabling precise editing at specific loci.
Tag: genome editing
A bacterial defense with potential application in genome editing
Scientists who have described in a new study the step-by-step details of a bacterial defense strategy see the mechanism as a promising platform for development of a new genome-editing method.
MSU discovers method for CRISPR-based genome editing in Nile grass rats
A team of researchers at Michigan State University has discovered a set of methods that enabled the first successful CRISPR-based genome editing in Nile grass rats.
Researchers at Phoenix Children’s First in the World to Produce Mouse Lungs in Rats
Research conducted at the Phoenix Children’s Research Institute at the University of Arizona College of Medicine — Phoenix reports the successful generation of a mouse lung in a rat, according to a paper published in the American Journal of Respiratory and Critical Care Medicine.
Creating a Virus-Resistant Bacterium Using a Synthetic Engineered Genome
To improve bioproducts productivity, researchers have engineered the genome of E. coli to make it immune to viral infections.
Groundbreaking genome editing tools unlock new possibilities for precision medicine
Traditional genome editing faced limitations in achieving ultimate precision until now. Prof. Buchholz’s team has broken through this barrier by creating what many have sought after: a zinc-finger conditioned recombinase.
New discovery set to boost disease-resistant rice
Rice that is resistant to some of the worst crop-destroying diseases but can still produce large yields could soon become a reality for farmers worldwide. A University of Adelaide researcher is part of an international team which has identified a new gene variant in a type of rice that can be modified to improve the performance of the crop.
Researchers discover a way to improve nonviral gene editing as well as a new type of DNA repair
Gene editing is a powerful method for both research and therapy. Since the advent of the Nobel Prize-winning CRISPR/Cas9 technology, a quick and accurate tool for genome editing discovered in 2012, scientists have been working to explore its capabilities and boost its performance.
Dana Carroll receives 2023 Rosenblatt Prize for Excellence
Dana Carroll, distinguished professor in the Department of Biochemistry in the Spencer Fox Eccles School of Medicine at the University of Utah, is the 2023 recipient of the Rosenblatt Prize for Excellence in recognition of his pioneering work in genome editing. The Rosenblatt Prize is the University of Utah’s highest faculty accolade and is presented annually to a faculty member who transcends ordinary teaching, research and administrative contributions.
How to turn specific genes on and off
Type 1 diabetes, rheumatoid arthritis, and cancer are just some of the disorders associated with specific genes not “turning on” and “turning off” as they should.
When organoids meet coronaviruses
Researchers from the group of Hans Clevers in collaboration with the group of Bart Haagmans (Erasmus MC) established an organoid biobank to search for the genes that are essential for the spreading of a SARS-CoV2 infection.
Building a better green workhorse
Biologists at Washington University in St. Louis lead a team awarded $1.7 million from the National Science Foundation to streamline the genome of a cyanobacterium with the goal of developing a green cellular factory for sustainable production of food, feed and fuels.
Jennifer Doudna Awarded 2020 Nobel Prize in Chemistry
The Royal Swedish Academy of Sciences announced today that Howard Hughes Medical Institute (HHMI) Investigator Jennifer Doudna of University of California, Berkeley, and Emmanuelle Charpentier of the Max Planck Unit for the Science of Pathogens are the recipients of the 2020 Nobel Prize in Chemistry for the development of a method for genome editing.
Jennifer Doudna Wins 2020 Nobel Prize in Chemistry
Biochemist Jennifer Doudna, a professor at UC Berkeley and faculty scientist at the Department of Energy’s Lawrence Berkeley National Laboratory (Berkeley Lab), is co-winner of the 2020 Nobel Prize in Chemistry for “the development of a method for genome editing.”