Article title: Mechanisms driving fasting-induced protection from genotoxic injury in the small intestine Authors: Kali Deans-Fielder, Timothy Wu, Thanh Nguyen, Sarah To, Yang-Zhe Huang, Steven J. Bark, Jason C. Mills, Noah F. Shroyer From the authors: “Our results also showed…
Tag: Doxorubicin
Pediatric hepatoblastoma model hints at DNA damage repair pathway for novel therapeutics
Scientists at St. Jude Children’s Research Hospital used genomics to inform the creation of genetic and new cell-line models for hepatoblastoma, which pointed toward the DNA damage repair pathway as a promising therapeutic route.
A New Method to Test Cancer Drug Toxicity
A new study from researchers at Cummings School of Veterinary Medicine at Tufts University and Tufts Medical Center reports that heart tissue obtained through organ donations from dogs dying of other causes are a promising platform for testing cancer drug toxicity, offering scientists a new alternative.
Shih-Ting (Christine) Wang: Designing Materials for Biomedicine
Using DNA-based assembly, the Center for Functional Nanomaterials postdoc has assembled functional proteins into ordered lattices and coated nanostructures for drug delivery.
Finding a way to stop chemotherapy from damaging the heart
There could be an intervention on the horizon to help prevent heart damage caused by the common chemotherapy drug doxorubicin, new research suggests.
Calcium bursts kill drug-resistant tumor cells
Researchers reporting in ACS’ Nano Letters have developed nanoparticles that release bursts of calcium inside tumor cells, inhibiting drug pumps and reversing MDR.