Penn Study Paves Way for New Vaccines to Protect Infants Against Infections

A new Penn Medicine study puts researchers within closer reach of vaccines that can protect infants against infections by overcoming a mother’s antibodies, which are known to shut down immune defenses initiated by conventional vaccines. That hurdle largely explains why vaccinations for infectious diseases like influenza and measles not given until six to 12 months of age. Findings from the preclinical study were published online today in Science Translational Medicine.

Start of phase II clinical trial in four types of terminal cancers

December 15, 2019 N. N. The Alexandrov National Cancer Centre begins phase II case-control clinical trial of its immuno-oncology agent, Elenagen. Inoperable late-stage cancer patients with triple-negative breast cancer, ovarian cancer, stomach cancer or prostate cancer will be randomized and…

Researchers develop universal flu vaccine that protects against 6 influenza viruses in mice

ATLANTA–A novel nanoparticle vaccine that combines two major influenza proteins is effective in providing broad, long-lasting protection against influenza virus in mice, showing promise as a universal flu vaccine, according to a study by the Institute for Biomedical Sciences at…

Start of phase II clinical trial in four types of terminal cancers

December 15, 2019 N. N. The Alexandrov National Cancer Centre begins phase II case-control clinical trial of its immuno-oncology agent, Elenagen. Inoperable late-stage cancer patients with triple-negative breast cancer, ovarian cancer, stomach cancer or prostate cancer will be randomized and…

Researchers develop universal flu vaccine that protects against 6 influenza viruses in mice

ATLANTA–A novel nanoparticle vaccine that combines two major influenza proteins is effective in providing broad, long-lasting protection against influenza virus in mice, showing promise as a universal flu vaccine, according to a study by the Institute for Biomedical Sciences at…

Delivering TB Vaccine Intravenously Dramatically Improves Potency, Study Shows

Worldwide, more people die from tuberculosis than any other infectious disease, even though the vast majority were vaccinated. The vaccine just isn’t that reliable. But a new Nature study finds that simply changing the way the vaccine is administered could dramatically boost its protective power.

California’s stricter vaccine exemption policy and improved vaccination rates

California’s elimination, in 2016, of non-medical vaccine exemptions from school entry requirements was associated with an estimated increase in vaccination coverage at state and county levels, according to a new study published this week in PLOS Medicine by Nathan Lo…

Immune mystery solved in mice points to better protection from rotavirus in humans

Researchers at the University of Toronto have discovered how a brief disruption to a molecular pathway in the guts of mice before they are born can compromise adult immunity to a common and often deadly intestinal virus. The researchers found…

Immune mystery solved in mice points to better protection from rotavirus in humans

Researchers at the University of Toronto have discovered how a brief disruption to a molecular pathway in the guts of mice before they are born can compromise adult immunity to a common and often deadly intestinal virus. The researchers found…

Shigella strain resistant to all oral antibiotics circulating in Victoria

Researchers have reported an extremely drug-resistant strain of Shigella circulating in Victoria with the vast majority of cases occurring in men who have sex with men. Shigella could previously be treated by oral antibiotics at home, the strain identified by…

Shigella strain resistant to all oral antibiotics circulating in Victoria

Researchers have reported an extremely drug-resistant strain of Shigella circulating in Victoria with the vast majority of cases occurring in men who have sex with men. Shigella could previously be treated by oral antibiotics at home, the strain identified by…