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UrduNeutrophils are an important type of white blood cell that help your immune system fight infections. One of the many ways neutrophils help is by capturing germs in sticky, spider web-like structures called neutrophil extracellular traps, or NETs.However, excessive formation of NETs is seen in many autoimmune diseases as a sign of exuberant inflammation.
Tag: Neutrophils
Pathologists awarded grant from American Society of Hematology
Dr. Zhen Mei, a clinical pathologist, and Dr. Vivian Chang, a pediatric hematologist-oncologist, both at UCLA Health, have been awarded $30,000 from the American Society of Hematology to revise blood cell ranges for people with Duffy-null Associated Neutrophil Count, which is also known as Duffy-negative
PFAS Can Suppress White Blood Cell’s Ability to Destroy Invaders
In a new study, researchers found that the PFAS chemical GenX suppresses the neutrophil respiratory burst – the method white blood cells known as neutrophils use to kill invading pathogens.
Turning white blood cells into medicinal microrobots with light
Researchers reporting in ACS Central Science have used lasers to precisely control neutrophils — a type of white blood cell — as a natural, biocompatible microrobot in living fish. The “neutrobots” performed multiple tasks, showing they could someday deliver drugs to precise locations in the body.
‘Fortunate Accident’ May Yield Immunity Weapon Against Antibiotic-Resistant Bacteria
In what turned out to be one of the most important accidents of all time, Scottish bacteriologist Alexander Fleming returned to his laboratory after a vacation in 1928 to find a clear zone surrounding a piece of mold that had infiltrated a petri dish full of Staphylococcus aureus (S. aureus), a common skin bacterium he was growing.
Could neutrophils be the secret to cancer’s Achilles’ heel?
A study published in the June 10, 2021 issue of Cell describes a remarkable new mechanism by which the body’s own immune system can eliminate cancer cells without damaging host cells. The findings have the potential to develop first-in-class medicines that are designed to be selective for cancer cells and non-toxic to normal cells and tissues.
Researchers discover new particle in the blood of septic patients
Researchers at La Jolla Institute for Immunology (LJI) have found that people with sepsis have never-before-seen particles in their blood. The scientists are the first to show that these particles, called elongated neutrophil-derived structures (ENDS), break off of immune cells and change their shape as they course through the body.
DNA webs may drive lung pathology in severe COVID-19
Sticky webs of DNA released from immune cells known as neutrophils may cause much of the tissue damage associated with severe COVID-19 infections, according to two new studies published September 14 in the Journal of Experimental Medicine (JEM). The research, conducted by independent groups in Belgium and Brazil, suggests that blocking the release of these DNA webs could be a new therapeutic target for the management of severe forms of COVID-19.
UofL immunologist discovers biomarker warning of cellular crisis that could cause death in COVID-19 patients
UofL researchers have discovered that one type of immune cells, low-density inflammatory neutrophils, became highly elevated in some COVID-19 patients whose condition became very severe. This elevation signaled a point of clinical crisis and increased likelihood of death within a few days.