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UrduAge-related changes in the fibroblasts, cells that create the skin’s structure, contribute to the development of aggressive, treatment-resistant melanoma in males, according to research in mice by the Johns Hopkins Kimmel Cancer Center.
Tag: Fibroblasts
Exosomes from umbilical cord mesenchymal stromal cells promote the collagen production of fibroblasts from pelvic organ prolapse
BACKGROUNDPelvic organ prolapse (POP) involves pelvic organ herniation into the vagina due to pelvic floor tissue laxity, and vaginal structure is an essential factor. In POP, the vaginal walls exhibit abnormal collagen distribution and dec
UTEP Pharmacy Researchers Develop Potential Treatment for Fibrosis
Researchers at The University of Texas at El Paso are developing a new therapeutic approach that uses nanoparticles for the treatment of skin and lung fibrosis, conditions that can result in severe damage to the body’s tissues.
Fibroblasts in the penis are more important for erectile function than previously thought
Regular erections could be important for maintaining erectile function, according to a new study on mice published in Science by researchers at Karolinska Institutet.
Promising heart drugs ID’d by cutting-edge combo of machine learning, human learning
University of Virginia scientists have developed a new approach to machine learning – a form of artificial intelligence – to identify drugs that help minimize harmful scarring after a heart attack or other injuries.
How cells are influenced by their environment as tissues grow
How does an embryo develop? How do children grow, wounds heal or cancer spread? All of this has to do with the growth of body tissue.
Simulating Cuts and Burns Reveals Wound Healing and Clearing Power of Fibroblasts
In APL Bioengineering, researchers create a biomimetic model to study wound healing in burn and laceration wounds. The team designed an in vitro model system made of fibroblasts embedded in a collagen hydrogel. Wounds were created in this microtissue using a microdissection knife to mimic laceration or a high-energy laser to simulate a burn. They discovered that fibroblasts clear away damaged tissue before depositing new material. This part of the healing process is slower in burn wounds.