Newly-published NCCN Guidelines for Pediatric Central Nervous System Cancers synthesize latest evidence to help care teams ensure children with high-grade gliomas have best possible outcomes; available free at NCCN.org.
Tag: Central Nervous System (CNS)
Brain Cell Activity Plays Critical Role in CNS Disorder Outcomes
Investigators at Cedars-Sinai have comprehensively mapped molecular activity in the brain and spinal cord that is responsible for regulating the body’s response to central nervous system (CNS) disorders such as Alzheimer’s, Huntington’s disease and spinal cord injuries.
A Trio That Could Spell Trouble: Many with Dementia Take Risky Combinations of Medicines
People over 65 shouldn’t take three or more medicines that act on their brain and nervous system, experts strongly warn, because the drugs can interact and raise the risk of everything from falls to overdoses to memory issues.
But a new study finds that 1 in 7 people with dementia who live outside nursing homes are taking at least three of these drugs.
Astrocytes offer potential drug targets for Huntington’s disease
UCLA scientists discovered that astrocytes, a cell type long implicated in brain diseases, is remarkably malleable and shows responses in a mouse model that suggest potential targets for drugs for Huntington’s disease.
IL-21 protein a key part of immune response to central nervous system infections
Researchers at Penn State College of Medicine now better understand the role of a protein, interleukin-21 (IL-21), in the immune system response to infections in the nervous system.
How herpes simplex virus can evade the immune response to infect the brain
A research team has discovered a molecular mechanism that helps Herpes simplex virus (HSV1) evade the innate immune system and infect the brain causing a rare disease with high mortality. The study from Aarhus University, University of Oxford, and University of Gothenburg, led by first author Chiranjeevi Bodda in Søren Paludan’s lab, will be published May 8 in the Journal of Experimental Medicine (JEM).
Nanocapsule reaches cancer that has spread to central nervous system in mice
Researchers developed a drug delivery system that can break through the blood-brain barrier in mice.