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UrduDrugs that selectively kill senescent cells may benefit otherwise healthy older women but are not a “one-size-fits-all” remedy, Mayo Clinic researchers have found. Specifically, these drugs may only benefit people with a high number of senescent cells, according to findings publishing July 2 in Nature Medicine.
Tag: Senescent cells
Nicolas Musi, MD, Named Inaugural Cypres Chair in Diabetes Research
Nicolas Musi, MD, studies a spectrum of age-related disorders that can impact a healthy lifespan.
Study Explains How “Zombie” Cancer Cells Revive Themselves
One protein brings inactive colorectal cancers back to life, but drugs could block it, Rutgers researchers find.
Retrospective study finds that cancer drug also lowers blood glucose
Dasatinib, a drug that often is used to treat certain types of leukemia, may have antidiabetic effects comparable to medications used to treat diabetes, and with more research may become a novel therapy for diabetic patients, according to new research published in Mayo Clinic Proceedings.
Senolytics reduce COVID-19 symptoms in preclinical studies
Mayo Clinic researchers and colleagues at the University of Minnesota showed that COVID-19 exacerbates the damaging impact of senescent cells in the body. In preclinical studies, the senolytic drugs discovered at Mayo significantly reduced inflammation, illness, and mortality from COVID infection in older mice. The findings appear in the journal Science.