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UrduRockville, Md. (April 19, 2024)—Blocking a specific calcium channel called CM4620 may become a new way to treat the life-threatening inflammatory disease acute pancreatitis. While this therapy appears to be the first effective treatment for acute pancreatitis, it has yet…
Tag: acute pancreatitis
A Novel Mechanism May Be Effective in Patients With Severe Hypertriglyceridemia and Prior Episodes of Acute Pancreatitis
A novel type of therapy, known as ANGPTL3 inhibitor therapy, was effective in lowering triglycerides in certain types of patients with severe hypertriglyceridemia (sHTG) who had a prior episode(s) of acute pancreatitis. sHTG is a well-established risk factor for recurrent episodes of acute pancreatitis. These high-risk patients were the focus of a phase 2 study that was led by the Icahn School of Medicine at Mount Sinai and sponsored and funded by Regeneron.
Alcoholic Pancreatitis Patients with Continued Alcohol Intake May Finally Have Therapeutic Options
Researchers at the Miller School are looking for solutions to the continued effects of alcohol use, its harmful impact, and treatment. Understanding the mechanisms of alcohol abuse has gained importance, especially after the COVID-19 pandemic. Higher alcohol consumption led to an increased burden of pancreatic diseases in society.
Study Shows Significant Reduction in Triglycerides in Patients at High Risk for Acute Pancreatitis Through Novel Monoclonal Antibody
The investigational drug evinacumab reduced triglycerides in patients with severe hypertriglyceridemia (sHTG) and a history of hospitalizations for acute pancreatitis in a phase 2 global study led by Mount Sinai