Article title: CFTR and PC2, partners in the primary cilia in autosomal dominant polycystic kidney disease Authors: Murali K. Yanda, Cristian Ciobanu, William B. Guggino, Liudmila Cebotaru From the authors: “Here we show that [cystic fibrosis transmembrane conductance regulator (CFTR)]…
Tag: Renal Disease
Making a Dent in Dent Disease: Researchers Explore Current Literature, Ask More Questions
Dent disease is a rare kidney disorder characterized by excess protein in the urine (proteinuria) caused by mutation of the chloride/proton exchanger ClC-5. People with Dent disease often develop chronic kidney disease that progresses to end-stage kidney disease. A new…
Sacubitril and Valsartan Combination Treatment May Reduce Hypertensive Kidney Disease
Article title: Differential effects of low-dose sacubitril and/or valsartan on renal disease in salt-sensitive hypertension Authors: Iuliia Polina, Mark Domondon, Rebecca Fox, Anastasia V. Sudarikova, Miguel Troncoso, Valeriia Y. Vasileva, Yuliia Kashyrina, Monika Beck Gooz, Ryan S. Schibalski, Kristine Y.…
Lack of Sodium Channel Component Protects against Diet-induced Artery Stiffening
Article title: Western diet induces renal artery endothelial stiffening that is dependent on the epithelial Na+ channel Authors: Yuxin Xiong, Annayya R. Aroor, Francisco I. Ramirez-Perez, Guanghong Jia, Javad Habibi, Camila Manrique-Acevedo, Guido Lastra, Donqqing Chen, Vincent G. DeMarco, Luis A.…
University Hospitals Employee Offers to Donate Kidney within Ten Minutes of Meeting Patient in Need
Erika Hosey, a cardiovascular technician at University Hospitals Ahuja Medical Center, ended the year by giving a life-changing gift to a patient in need. While performing a routine cardiac stress test, she drummed up a conversation. She learned that her patient, Denise Butvin, had kidney disease and needed transplant surgery.
“Erika just blurted out…I’ll give you my kidney,” said Butvin. “I was in shock. I couldn’t believe this was real.”
While Butvin is a positive person, she has been through an emotional rollercoaster of ups and downs and on waitlists in Ohio and Pennsylvania for five years. Her family and friends were not an organ match. Both her sister and father were on dialysis for many years and passed away from kidney disease, so she knew how pressing this transplant surgery was.
Hosey started the process the next day, and after a few weeks of testing turned out to be a perfect donor match. “To be a kidney donor match for someone is really a shot in the dark,” she