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UrduRockville, Md. (August 22, 2024)—The ability of skeletal muscle to produce force (contractile function) and contraction-stimulated glucose uptake (increase in clearing sugar from bloodstream) do not differ by time of day, regardless of sex or muscle type. The first-of-its-kind study…
Tag: Function Journal
New Data Outlines Positive Effects of Endurance Exercise Training
Rockville, Md. (May 16, 2024)—Treadmill training, a form of endurance exercise, was found to be highly effective “with robust improvements in skeletal muscle citrate synthase activity in as little as [one to two] weeks, and improvements in maximum run speed…
New Research Challenges Link Between Motor Impairment and Brain Injury
Rockville, Md. —Motor impairment following brain injury has long thought to be purely anatomical, and that traumatic brain injury, stroke or other neurological injury results in abnormal muscle tightness and rigidity. Evidence of this belief is based on studies of…
Older Adults with Advanced Hypertension Should Be Careful with Certain Antihypertensive Medicines
Rockville, Md. (February 8, 2024)—Current data published in the journal Function “indicate caution against the use of L-type Ca2+ channel blockers in elderly patients or patients with advanced hypertension and/or onset of cardiovascular remodeling, where levels of STIM and ORAI…
Faulty Neurotransmitter Causes Weak, Overactive Bladder in Mice
Rockville, Md. (September 8, 2022)—Urinating more frequently and in lower volumes can be a sign of overactive bladder, according to physiologists from Beth Israel Deaconess Medical Center and Harvard Medical School in Boston. Researchers investigated how the smooth muscle in…
Marijuana Plant Might Hold Key to Treating Chronic Inflammation
Rockville, Md. (July 18, 2022)—Several minor cannabinoids contained in the cannabis plant “strongly inhibit” the activation of human immune cells that lead to chronic inflammation, according to physiologists at The Queen’s Medical Center and University of Hawaii. The study also…
New Exercise Technique Improves Muscle Responsiveness in Aging Mice
Rockville, Md. (June 1, 2022)—Combined modality exercise such as aerobic and resistance exercise is highly beneficial for an aging population, according to a new mouse study published ahead of print in the journal Function. Researchers also discovered the calf muscle…
Researchers Unexpectedly Identify Potential Causes of Asthma, COPD
Rockville, Md. (November 8, 2021)—The activation of muscarinic acetylcholine (M2) receptors could be one of the causes of diseases like asthma and chronic obstructive pulmonary disease (COPD), according to the findings of a new study in the journal Function. The…
Secondhand Smoke Impairs Heart Tissue Cells and Vascular Smooth Muscle Constriction
Rockville, Md. (August 26, 2021)—Chronic exposure to an “environmentally relevant concentration” of secondhand smoke (SHS) impairs mesenteric arterial myocyte electrophysiology (muscle cells within heart tissue) and myogenic tone (constriction of vascular smooth muscle), according to a new study conducted in…
Nucleus Type-specific DNA Methylomics Reveals Epigenetic ‘Memory’ of Prior Adaptation in Skeletal Muscle
Rockville, Md. (August 10, 2021)—New data from research conducted in adult mice show that distinct epigenetic (the study of changes in organisms) changes occur in muscle fiber and non-muscle fiber nuclei with exercise training, and that some DNA methylation alterations…
Over-expression of MuRF1 Protein Identified as Sufficient Cause of Muscle Wasting
Rockville, Md. (May 27, 2021)—Over-expression of the MuRF1 protein in the skeletal muscle of mice was sufficient to cause muscle wasting, according to a new study by researchers from the University of Iowa Carver College of Medicine. In addition, researchers…
New Kidney Function Research will Require Revision of Contemporary Medical Textbooks
Rockville, Md. (September 17, 2020)—Researchers have identified fundamental relationships between water and ion reabsorption, as well as cross talk between sugar reabsorption and fluid reabsorption as it relates to kidney functions. In addition, researchers concluded that the required balance between…