The effect of resting dendritic cells on overall survival in the hepatocellular carcinoma tumor microenvironment

Background: Hepatocellular carcinoma (HCC) continues to have a poor prognosis even in the advent of new immunotherapy regimens. An area of growing interest in HCC is its tumor immune microenvironment. Classifying the immune microenvironment based on available genomics can lead to…

Cancer patients who don’t respond to immunotherapy lack crucial immune cells

Cancer immunotherapy involves using activated T cells to destroy tumors, but it doesn’t work for all patients. Researchers at Washington University School of Medicine in St. Louis have discovered that a kind of dendritic cell is crucial for determining the effectiveness of immunotherapy. The discovery could lead to new ways to extend the benefits of immunotherapy to more patients.