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UrduUsing neutrons, researchers at Oak Ridge National Laboratory pieced together the molecular mechanics behind a peptide’s ability to deal significant damage to bacterial cells. Their findings could inform new therapeutic strategies for treating bacterial infections where antibiotics have fallen short.
Tag: Antimicrobial Peptides
Possible new antivirals against COVID-19, herpes
The immune system fights viruses with peptides. Now, scientists have treated animal models of herpes with synthetic peptide mimics known as peptoids. These molecules could one day cure or prevent many kinds of infections, including COVID-19. They will present their results at ACS Fall 2021.
CHOP Researchers Develop Coating for Endotracheal Tubes that Releases Antimicrobial Peptides
In a proof-of-concept study, researchers at Children’s Hospital of Philadelphia (CHOP) have created a coating that can be applied to endotracheal tubes and release antimicrobial peptides that target infectious bacteria with specificity. The innovation could reduce upper-airway bacterial inflammation during intubation, a situation that can lead to chronic inflammation and a condition called subglottic stenosis, the narrowing of the airway by an accumulation of scar tissue. The findings were published recently in the journal The Laryngoscope.