CHOP Researchers Develop Coating for Endotracheal Tubes that Releases Antimicrobial Peptides

In a proof-of-concept study, researchers at Children’s Hospital of Philadelphia (CHOP) have created a coating that can be applied to endotracheal tubes and release antimicrobial peptides that target infectious bacteria with specificity. The innovation could reduce upper-airway bacterial inflammation during intubation, a situation that can lead to chronic inflammation and a condition called subglottic stenosis, the narrowing of the airway by an accumulation of scar tissue. The findings were published recently in the journal The Laryngoscope.

The Mask Matters: How Masks Affect Airflow, Protection Effectiveness

Even though it has been widely known that wearing a face mask will help mitigate the community spread of COVID-19, less is known regarding the specific effectiveness of masks in reducing the viral load in the respiratory tracts of those wearing them. In Physics of Fluids, researchers examined the effect of wearing a three-layer surgical mask on inspiratory airflows and the mask’s effects on the inhalation and deposition of ambient particles in the upper respiratory airways.