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UrduThree recently published studies from Cedars-Sinai investigators have deepened knowledge of how changes in the eye are linked to indicators of Alzheimer’s disease in the brain.
Tag: Amyloid Plaques
Immunotherapy for Alzheimer’s disease shows promise in mouse study
Scientists at Washington University School of Medicine in St. Louis have shown that treating mice with an antibody that blocks the interaction between APOE proteins (white) sprinkled within Alzheimer’s disease plaques and the LILRB4 receptor on microglia cells (purple) activates them to clean up damaging plaques (blue) in the brain.
Study Suggests Alcohol Consumption Linked to Acceleration of Alzheimer’s Disease
In a new preclinical study, scientists at Wake Forest University School of Medicine showed that even modest amounts of alcohol can accelerate brain atrophy, which is the loss of brain cells, and increase the number of amyloid plaques, which are the accumulation of toxic proteins in Alzheimer’s disease.
Green Tea and Resveratrol Reduce Alzheimer’s Plaques in Lab Tests
Using a 3D model of a network of living brain cells, researchers found that two common compounds—green tea catechins and resveratrol found in red wine and other foods—reduced the formation of amyloid plaques linked to Alzheimer’s disease
Understanding Alzheimer’s Progression with Improvements to Imaging, Image Processing, Machine Learning
Because there is no ethical way to extract brain tissue from patients to look for clues about how amyloid plaques and protein aggregates proliferate, supplementary techniques are needed to better understand the progression of Alzheimer’s disease. During ACA’s 71st annual meeting, Abdullah Al Bashit, from Northeastern University, will discuss using computational techniques to help address these challenges. His work demonstrates how using small and wide-angle scattering along with state-of-the-art detection techniques will help probe the molecular structure and proliferation.
Novel Drug Prevents Amyloid Plaques, a Hallmark of Alzheimer’s Disease
Researchers at UC San Diego School of Medicine and elsewhere have identified a new drug that could prevent AD by modulating, rather than inhibiting, a key enzyme involved in forming amyloid plaques.