Diabetes Drug May Protect Breastfed Sons from Future Metabolic Disorder

Article title: Lactational metformin exposure programs offspring white adipose tissue glucose homeostasis and resilience to metabolic stress in a sex-dependent manner

Authors: Zach Carlson, Hannah Hafner, Molly Mulcahy, Kaylie Bullock, Allen Zhu, Dave Bridges, Ernesto Bernal-Mizrachi, Brigid Gregg

From the authors: “Future studies will focus on understanding how metformin causes these changes, whether indirectly through changes in milk composition, through changes in the colonization of the infant intestinal microbiome or through direct action on the offspring intestine or liver.”

This study is highlighted as one of May’s “best of the best” as part of the American Physiological Society’s APSselect program.

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