RNA Inhibitor Is Shown Safe and Effective in Reducing a Wide Range of Cholesterol and Triglyceride Levels in the Blood in Mount Sinai-Led Clinical Trial

A small interfering RNA (siRNA) investigational therapy that inhibits a gene involved in lipoprotein metabolism has been shown in a clinical trial led by Mount Sinai researchers to significantly reduce levels of different types of cholesterol and triglycerides in individuals with mixed hyperlipidemia, a condition in which fats build up in the blood.

Patients With Specific Types of Lipids May Be at Higher Risk of Developing Blinding Eye Disease

Principal Investigator: Louis R. Pasquale, MD, FARVO, Deputy Chair for Ophthalmology Research for the Mount Sinai Health System Co-First Authors: Oana A. Zeleznik, PhD, Instructor in Medicine at Brigham and Women’s Hospital and Jae H. Kang, ScD, Assistant Professor of…