Study reveals link between microbiome and aggression in mice

A new study led by Prof. Omry Koren and graduate student Atara Uzan-Yuzari from the Azrieli Faculty of Medicine at Bar-Ilan University has unveiled significant evidence connecting the gut microbiome to aggressive behavior in mice.

Published in the journal Brain, Behavior, and Immunity, the research explores how disruptions in the microbiome, particularly due to antibiotic use in early life, can lead to increased aggression.

UC Irvine to lead multi-institutional study of single-cell vulnerabilities to Alzheimer’s disease

The University of California, Irvine has received a five-year, $10 million grant from the National Institutes of Health to lead a multi-institutional study of specific brain cell vulnerabilities to abnormal tau protein deposits in regions affected in the early stages of Alzheimer’s disease.

Rethinking How Cancer Cells Evade Targeted Therapy

In a study publishing December 20 in Nature Cancer, UCSF researchers found that phenotype switching, as opposed to genetic evolution, may be the escape mechanism that explains the failure of precision therapies to date. They found that some cells shift to a mesenchymal, radiation-resistant phenotype (state) as a stress response following standard therapy.