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UrduBACKGROUNDMesenchymal stem cells (MSCs) have been extensively studied for therapeutic potential, due to their regenerative and immunomodulatory properties. Serial passage and stress factors may affect the biological characteristics of MSCs,
Tag: Senescence
Expansion of human umbilical cord derived mesenchymal stem cells in regenerative medicine
BACKGROUNDStem cells are undifferentiated cells that possess the potential for self-renewal with the capacity to differentiate into multiple lineages. In humans, their limited numbers pose a challenge in fulfilling the necessary demands for
A Common Diabetes Drug Has a Surprising Side Gig: Muscle Protector
You might not think of diabetes when you think of muscle function. But a common diabetes drug that regulates blood sugar can also prevent muscle atrophy and muscular fibrosis—which can help the elderly bounce back faster from injury or illness.
Study Explains How “Zombie” Cancer Cells Revive Themselves
One protein brings inactive colorectal cancers back to life, but drugs could block it, Rutgers researchers find.
New UCI-led study shows repeated stress accelerates aging of the eye
New research from the University of California, Irvine, suggests aging is an important component of retinal ganglion cell death in glaucoma, and that novel pathways can be targeted when designing new treatments for glaucoma patients.
Peter Adams and Bing Ren awarded $10.6M to create atlas of aging cells
Peter Adams, Ph.D., and Bing Ren, Ph.D., have been awarded a new grant from the National Institutes of Health (NIH) to join a multi-institution initiative studying the process of aging.
Aging Limits Lung Cells’ Ability to Regenerate after Injury
A new study in mice explores the effect of aging on the regenerative properties of lung cells after lung injury. The study is published in the American Journal of Physiology-Lung Cellular and Molecular Physiology. It was chosen as an APSselect article for November.
Aging Limits Lung Cells’ Ability to Regenerate after Injury
Article title: Aging impairs alveolar epithelial type II cell function in acute lung injury Authors: Tolga Yazicioglu, Christian Mühlfeld, Chiara Autilio, Cheng-Kai Huang, Christian Bär, Oliver Dittrich-Breiholz, Thomas Thum, Jesús Pérez-Gil, Andreas Schmiedl, Christina Brandenberger From the authors: “We show that…
University of Minnesota, Van Andel Institute earn $6M to study aging’s role in Parkinson’s
GRAND RAPIDS, Mich. (Sept. 21, 2020) — A collaborative team between the University of Minnesota Medical School and Van Andel Institute (VAI) will soon begin a $6.2 million study that seeks to define the molecular linkages between aging and Parkinson’s disease — an approach for new treatment targets not yet explored by many researchers. The group recently earned a three-year grant from the Aligning Science Across Parkinson’s initiative, an international collaborative research effort partnering with The Michael J. Fox Foundation for Parkinson’s Research to implement its funding.