Aging Limits Lung Cells’ Ability to Regenerate after Injury

Article title: Aging impairs alveolar epithelial type II cell function in acute lung injury

Authors: Tolga Yazicioglu, Christian Mühlfeld, Chiara Autilio, Cheng-Kai Huang, Christian Bär, Oliver Dittrich-Breiholz, Thomas Thum, Jesús Pérez-Gil, Andreas Schmiedl, Christina Brandenberger

From the authors: “We show that [acute lung injury] promotes cell senescence and limits regenerative capacity in [aleveolar epithelial type 2 cells] in old mice.”

This study is highlighted as one of November’s “best of the best” as part of the American Physiological Society’s APSselect program.