The immune system plays a key role in changing our behaviors in response to environmental dangers, a new Yale School of Medicine study finds. Researchers found ova-allergic mice lost their avoidance behavior to the egg protein when Immunoglobulin E antibodies,…
Tag: mouse studies
Scientists Find a Pair of Proteins Control Supply Lines That Feed Cancer Cells
In human cancer cell and mouse studies, researchers from Johns Hopkins Medicine have found that a set of proteins work in tandem to build supply lines that deliver oxygen and nutrients to tumors, enabling them to survive and grow. The protein twosome, PADI4 and HIF-1, ramp up their activity under low-oxygen conditions that are typically found in a fast-growing tumor, allowing it to build new blood vessels that feed the cancer’s growth.
New treatment shows promise in preventing heart failure after heart attack
A study in mice finds treatment with a molecule called MCB-613 repairs heart tissue after a severe heart attack, preventing damage that can lead to heart failure. The findings are being presented virtually at ENDO 2021, the Endocrine Society’s annual meeting.