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UrduA protein called Meteorin-like (METRNL) in the tumor microenvironment saps energy from T cells, thereby severely limiting their ability to fight cancer.
Tag: Mitochondria and cancer
Wistar Scientists Identify Link Between Mitochondria and Pancreatic Cancer Risk
In a research paper published in PLOS ONE, The Wistar Institute’s Dario C. Altieri, M.D., alongside national and international collaborators, distinguish a specific gene signature indicative of mitochondrial reprogramming in tumors that correlates with poor patient outcome.
Breast Cancer Cells Use Message-carrying Vesicles to Send Oncogenic Stimuli to Neighboring Normal Cells
According to a Wistar study, breast cancer cells starved for oxygen send out messages that induce oncogenic changes in surrounding normal epithelial cells.
Identification of a Novel Regulator of Mitochondrial Cell Death Reveals a Promising Target for Cancer Therapy
Wistar researchers have described the role of mitochondrial fission factor (MFF) in controlling survival of cancer cells, suggesting the protein could represent a promising therapeutic target.
2019 Frontiers in Metabolism meeting explores advances in metabolic research
This fall, the Morgridge Institute for Research will convene international leaders in metabolic research at the third Frontiers in Metabolism—Mechanisms of Metabolic Diseases meeting. Disrupted metabolic processes underlie a broad swath of rare inborn errors of metabolism and prominent human…