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UrduA retrospective cohort study aimed to determine the associations between pre-transplant Epstein–Barr virus (EBV)–seronegative recipients of EBV-seropositive donor (EBV D+ /R-) and recipient EBV-seropositive status (R+) and incidence of posttransplant lymphoproliferative disorder (PTLD) among adult kidney transplant recipients.
Tag: Epstein Barr Virus
People with Long COVID Have Distinct Hormonal and Immune Differences From Those Without This Condition
Research conducted at Mount Sinai and Yale confirms long COVID is a biological disease by showing blood biomarkers that can predict who has it
Wistar Researchers Discover Potential Target for Gastric Cancers Associated with Epstein-Barr Virus
Now, scientists at The Wistar Institute have discovered a potential target for gastric cancers associated with Epstein-Barr Virus; study results were published in the journal mBio.
Long Covid not caused by COVID-19 immune inflammatory response, new research finds
Long Covid, which affects nearly two-million people in the UK (1), is not caused by an immune inflammatory reaction to COVID-19, University of Bristol-led research finds. Emerging data demonstrates that immune activation may persist for months after COVID-19.
Why Do Some Long Covid Patients Continue to Have Difficulty Exercising?
In a study published in the Journal of Infectious Diseases, a team of researchers from UC San Francisco found that lower than expected exercise capacity was common among people with Long COVID and chronotropic incompetence (inadequate heart rate increase during exercise) was the most common reason. They also found reduced exercise capacity to be correlated with early post-Covid elevations of inflammatory biomarkers. In addition, they found that reactivation of Epstein-Barr virus (EBV) may be related to reduced heart rate while exercising.
How Are Epstein-Barr Virus and Multiple Sclerosis (MS) Connected?
The linking of MS and EBV could be a significant step in gaining the upper hand in the prevention of MS, which affects nearly 1 million people over the age of 18 in the United States.
How Do Cancer-Causing Viruses Evade Immune Responses?
This research suggests that BAF and related proteins could be therapeutic targets to prevent these viruses from spreading and leading to cancers, such as Kaposi sarcoma, non-Hodgkin lymphoma, Hodgkin lymphoma, multicentric Castleman disease, nasopharyngeal carcinoma, and gastric cancer.
Monitoring Epstein-Barr viral load after liver transplant may reduce risk for rare posttransplant complication
A study of adult recipients of liver transplants has found that monitoring transplant recipients for Epstein-Barr virus viral load (EBV VL) helped to reduce risk for posttransplant lymphoproliferative disease (PTLD), a rare but serious potential complication of transplantation. The findings are published in Annals of Internal Medicine.
Wistar Scientists Make Pivotal Discovery on the Mechanism of Epstein-Barr Virus Latent Infection
Wistar researchers have discovered a new enzymatic function of the Epstein-Barr Virus (EBV) protein EBNA1, a critical factor in EBV’s ability to transform human cells and cause cancer. Published in Cell, this study provides new indications for inhibiting EBNA1 function, opening up fresh avenues for development of therapies to treat EBV-associated cancers.