Nature Reviews Nephrology published a landmark international consensus statement titled “Chronic Kidney Disease and the Global Public Health Agenda: An International Consensus.” Authored by a coalition of leading experts, stakeholders, and nephrology societies, the publication highlights critical policy, advocacy, and implementation needs to alleviate the growing burden of kidney disease worldwide.
Tag: chronic kidney disease (CKD)
Even lower levels of albuminuria associated with increased risk for CKD progression and kidney failure
A study of patients with chronic kidney disease (CKD) found substantial excess risk for CKD progression and kidney failure as albuminuria (protein in the urine) increased even at levels below 30 mg/g.
Unveiling uremic toxins linked to itching in hemodialysis patients
Dr. Yamamoto et al. found the several uremic toxins as one of causes of itching in hemodialysis patients.
Measuring eGFR based on cystatin C levels may be a more accurate assessment of kidney function in older adults
A study of more than 82,000 older adults receiving outpatient measurements of estimated glomerular filtration rate (eGFR) found that measuring eGFR based on creatinine and cystatin C levels (eGFRcr-cys) was more strongly associated with adverse outcomes than measuring eGFR with only creatinine levels (eGFRcr).
Acute kidney injury not associated with worsening kidney function in persons with CKD
A study of hospitalized persons with chronic kidney disease (CKD) fournd that acute kidney injury (AKI) did not predict worsening of kidney function trajectory once difference in pre-hospitalization characteristically were fully accounted for. Instead, the authors suggest that much of determinants of faster kidney disease decline observed after AKI may already be present before AKI. The findings are published in Annals of Internal Medicine.
Screening all U.S. adults aged 35 and older for chronic kidney disease could be cost effective
A cost-effectiveness analysis of screening for chronic kidney disease (CKD) has found that screening all adults in the United States starting at age 35 could be cost-effective for the quality of life-years (QALY) gained. The analysis is published in Annals of Internal Medicine.
Decision-Making Tool for Older Adults with Chronic Kidney Disease Improves Choices
For many adults 70 years and older with advanced chronic kidney disease, choosing the optimal treatment plan is challenging. Multiple options exist, including initiating hemodialysis or peritoneal dialysis, which may be associated with marginal survival advantages but significant quality of…
Digital decision aid may help older adults with CKD make better quality treatment decisions
A randomized controlled trial of 400 adults aged 70 years or older with chronic kidney disease (CKD) found that use of the decision-making aid DART (Decision-Aid for Renal Therapy) improved decision quality and clarified treatment preferences among older adults with advanced CKD for 6 months after the DART intervention. The findings are published in Annals of Internal Medicine.
Dapagliflozin reduces risk for hospitalization in patients with CKD with or without diabetes
Dapagliflozin, a sodium-glucose cotransporter-2 (SGLT2) inhibitor, reduced the risk for hospitalization for any cause in patients with chronic kidney disease (CKD) with and without type 2 diabetes.