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UrduWorking in organoid models, researchers at University of California San Diego School of Medicine have developed a new tool to study protein-kinase C (PKC) enzymes, which play a critical role in cell growth, differentiation and survival. Malfunction of these proteins…
Tag: Cell Growth
Cancer-causing mutations rewire growth signalling in prostate cancer model
Experts in cell signalling at the Babraham Institute have identified how prostate cancer cells achieve cell growth free from the usual growth cues and regulators.
Skin injury promotes healthy-cell expansion, helps control mutated cell growth
Healthy human skin is a mosaic of normal and mutation-bearing cells. More cells accumulate more mutations as we age, increasing skin cancer risk. Researchers in the lab of Valentina Greco found injury to the skin promotes healthy-cell expansion, which in…
Mechanism resembling ageing and cancer found in a Finnish mitochondrial disease
GRACILE syndrome, a mitochondrial disease that is part of the Finnish disease heritage, shows altered cell metabolism and proliferation resembling that of cancer cells.
How cells are influenced by their environment as tissues grow
How does an embryo develop? How do children grow, wounds heal or cancer spread? All of this has to do with the growth of body tissue.
Beyond the average cell
Models based on an average cell are useful, but they may not accurately describe how individual cells really work. New possibilities opened up with the advent of single-cell live imaging technologies. Now it is possible to peer into the lives of individual cells. In a new paper in PLOS Genetics, a team of biologists and physicists from Washington University in St. Louis and Purdue University used actual single-cell data to create an updated framework for understanding the relationship between cell growth, DNA replication and division in a bacterial system.
How a Shape-Shifting Receptor Influences Cell Growth
Receptors found on cell surfaces bind to hormones, proteins, and other molecules, helping cells respond to their environment.
Engineers grow pancreatic “organoids” that mimic the real thing
MIT engineers, in collaboration with scientists at Cancer Research UK Manchester Institute, have developed a new way to grow tiny replicas of the pancreas, using either healthy or cancerous pancreatic cells.
Researchers use lasers and molecular tethers to create perfectly patterned platforms for tissue engineering
University of Washington researchers developed a technique to modify naturally occurring biological polymers with protein-based biochemical messages to affect cell behavior. Their approach uses near-infrared lasers to trigger chemical adhesion of proteins to scaffolds made from biological polymers like collagen.