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UrduAnimal models don’t consistently recapitulate human CDKL5 deficiency disorder (CDD), a rare form of epilepsy. Using personalized brain organoids — “mini-brains” in a lab dish derived from stem cells of patients deficient in CDKL5 protein — researchers at UC San…
Tag: Molecular Medicine
Kawate lab unveils structure of major membrane protein
In a paper published on Feb 12 in the journal eLife, Dr. Toshimitsu Kawate, associate professor in the Department of Molecular Medicine and his team reveal the form of pannexin1, a cellular membrane protein present in all vertebrates. With the size, shape and formation of this protein revealed for the first time, scientists can get closer to fine tuning new therapies for a multitude of diseases, including chronic pain, infertility and cancer.