A first-of-its-kind study identifies mechanisms that explain how a drug commonly used to treat HIV and hepatitis causes kidney disease and kidney injury. The study is published ahead of print in Function.
Tag: mitochondrial function
Protein Deficiency Impairs Muscle Clock, Mitochondrial Function in Muscular Dystrophy
Article title: Dystrophin deficiency disrupts muscle clock expression and mitochondrial quality control in mdx mice Authors: Justin P. Hardee, Marissa K. Caldow, Audrey S.M. Chan, Stuart K. Plenderleith, Jennifer Trieu, Rene Koopman, Gordon S. Lynch From the authors: “These findings suggest that…
Organ Rejection Drug Rapamycin May Improve Cellular Health, Function in Myopathy Patients
Article title: Effect of rapamycin on mitochondria and lysosomes in fibroblasts from patients with mtDNA mutations Authors: Nashwa J. Cheema, Jessie M. Cameron, David A. Hood From the authors: “Treatment of [mitochondrial encephalopathy lactic acidosis stroke-like episodes] fibroblasts with rapamycin for…
Study Explores Mitochondrial Resilience in Adult Heart after Ablation
Article title: Mitochondrial functional resilience after TFAM ablation in the adult heart Authors: Nasab Ghazal, Jessica N. Peoples, Tahmina A. Mohiuddin, Jennifer Q. Kwong From the authors: “Our study highlights the need to delineate mitochondrial maintenance pathways in both developing…
Tissue Repair, Mitochondrial Function and Wound Healing Explored in 2021 APS President’s Symposium
Top researchers in physiology will present a three-part series exploring cellular regulation of mitochondrial function, tissue repair and wound healing. The APS President’s Symposium Series will be part of the APS annual meeting at Experimental Biology 2021, which will be held on a virtual platform April 27–30.