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UrduResearchers at Children’s Hospital of Philadelphia (CHOP) and the University of California, Los Angeles (UCLA) have developed a computational platform capable of discovering tumor antigens derived from alternative RNA splicing, expanding the pool of cancer immunotherapy targets. The tool, called “Isoform peptides from RNA splicing for Immunotherapy target Screening” (IRIS), was described in a paper published today in the Proceedings of the National Academy of Sciences.
Tag: Immunotherapy research
Natural killers: Using the body’s cells to target breast cancer
The research utilizes the body’s natural killer cells, part of the human immune system, to target breast cancer tumor cells. The triggers are fusion proteins developed by Clemson University researchers that link the two together. The research is a novel approach to developing breast cancer-specific immunotherapy.