Cedars-Sinai Guerin Children’s is building a formidable pediatric research enterprise aimed at identifying the genetic underpinnings of childhood diseases and developing novel therapies.
Tag: functional genomics
Revealing the Mysteries Within Microbial Genomes
A new technique developed at Berkeley Lab will make it much easier for researchers to discover the traits or activities encoded by genes of unknown function in microbes, a key step toward understanding the roles and impact of individual species within the planet’s diverse microbiomes.
CHOP Researchers Identify Causal Genetic Variant Linked to Common Childhood Obesity
Researchers have identified a causal genetic variant strongly associated with childhood obesity. The study provides new insight into the importance of the hypothalamus of the brain and its role in common childhood obesity and the target gene may serve as a druggable target for future therapeutic interventions.
UCSF Researchers Uncover New Pathway for Molecular Cancer Drug Therapies
In a study published December 8, 2022 in Science, UCSF researchers Kevin Lou, an MD-PhD student, Luke Gilbert, PhD, and Kevan Shokat, PhD, reveal the discovery of a cellular uptake pathway important for larger molecules. These large and complex molecules bind in unconventional ways to their targets, are efficiently taken up by target cells, and can be harnessed to create new drugs for the treatment of cancer and other diseases.