Discovery of Rapid COVID-19 Replication Mechanism and Expanded Treatment Options

Dr. Seong-Jun Kim’s team from the Korea Research Institute of Chemical Technology (KRICT) recently reported in a research paper that the rapid proliferation of COVID-19 is due to altered roles of mitochondria (responsible for energy production in human cells) and EGFR (responsible for growth signal transmission in cells).

Measuring eGFR based on cystatin C levels may be a more accurate assessment of kidney function in older adults

A study of more than 82,000 older adults receiving outpatient measurements of estimated glomerular filtration rate (eGFR) found that measuring eGFR based on creatinine and cystatin C levels (eGFRcr-cys) was more strongly associated with adverse outcomes than measuring eGFR with only creatinine levels (eGFRcr).

Medical Students Lead Nationwide Movement to Excise Racism From Nephrology Curricula

As medical schools across the country grapple with the arduous process of revising their curricula to be anti-racist, students at the Icahn School of Medicine at Mount Sinai have turned a critical eye on the very textbooks that have trained medical students for years.

Substantial discrepancies found between estimated and measured GFR

A cross sectional study found that substantial discrepancies exist between individual estimated glomerular filtration rate (eGFR) and directly measured GFR (mGFR). Laboratory reports that provide eGFR calculations should consider including the distribution of this uncertainty. According to the authors, renaming the eGFR as a population average GFR (or paGFR) merits further discussion. The findings are published in Annals of Internal Medicine.