Dr. Seong-Jun Kim’s team from the Korea Research Institute of Chemical Technology (KRICT) recently reported in a research paper that the rapid proliferation of COVID-19 is due to altered roles of mitochondria (responsible for energy production in human cells) and EGFR (responsible for growth signal transmission in cells).
Tag: EGFR
Measuring eGFR based on cystatin C levels may be a more accurate assessment of kidney function in older adults
A study of more than 82,000 older adults receiving outpatient measurements of estimated glomerular filtration rate (eGFR) found that measuring eGFR based on creatinine and cystatin C levels (eGFRcr-cys) was more strongly associated with adverse outcomes than measuring eGFR with only creatinine levels (eGFRcr).
Medical Students Lead Nationwide Movement to Excise Racism From Nephrology Curricula
As medical schools across the country grapple with the arduous process of revising their curricula to be anti-racist, students at the Icahn School of Medicine at Mount Sinai have turned a critical eye on the very textbooks that have trained medical students for years.
Substantial discrepancies found between estimated and measured GFR
A cross sectional study found that substantial discrepancies exist between individual estimated glomerular filtration rate (eGFR) and directly measured GFR (mGFR). Laboratory reports that provide eGFR calculations should consider including the distribution of this uncertainty. According to the authors, renaming the eGFR as a population average GFR (or paGFR) merits further discussion. The findings are published in Annals of Internal Medicine.
National Kidney Foundation and the American Society of Nephrology Release New Way to Diagnose Kidney Diseases
Today, the National Kidney Foundation (NKF) and the American Society of Nephrology (ASN) Task Force on Reassessing the Inclusion of Race in Diagnosing Kidney Diseases has released its final report, which outlines a new race-free approach to diagnose kidney disease.
Novel Therapy Shows Promise for Lung Cancer Patients with Rare EGFR Mutation
Moffitt Cancer Center is part of a multinational, early phase clinical trial evaluating a new targeted therapy for patients with metastatic or unresectable non-small cell lung cancer who have a specific genetic mutation: EGFR Ex20Ins. New expanded data from the trial was published in the Journal of Clinical Oncology.
Target Discovered That Halts Osteoarthritis-Like Knee Cartilage Degeneration
In a mouse study, researchers used nanotechnology and previous knowledge of a protein pathway to significantly reduce knee cartilage degeneration and pain
Dana-Farber Cancer Institute to Establish Chen-Huang Center for EGFR Mutant Lung Cancers
Dana-Farber Cancer Institute will create the Chen-Huang Center for EGFR (epidermal growth factor receptor) Mutant Lung Cancers to stimulate research, promote clinical trials, and strengthen the Institute’s capabilities for studying and treating lung cancer.