T Cell Therapy, Gut Microbiome, Tumorigenicity, and More Featured in September 2020 Toxicological Sciences

The September 2020 issue Toxicological Sciences—Volume 177, Issue 1—is now available, featuring leading research in toxicology in the areas of biomarkers, environmental toxicology, and more.

The September edition includes three Tox Spotlight articles:

• “A Positive Feedback Loop Between c-Myc Upregulation, Glycolytic Shift, and Histone Acetylation Enhances Cancer Stem Cell-Like Property and Tumorigenicity of Cr(VI)-Transformed Cells”
• “Nonclinical Safety Assessment of AMG 553, an Investigational Chimeric Antigen Receptor T-Cell Therapy for the Treatment of Acute Myeloid Leukemia”
• “Gut Microbiome Critically Impacts PCB-Induced Changes in Metabolic Fingerprints and the Hepatic Transcriptome in Mice” 

ToxSci Contemporary Reviews, “provide expert analysis of important and emerging areas in the field of toxicology. This issue includes a Contemporary Review exploring “Broad Spectrum Treatment for Ocular Insult Induced by Organophosphate Chemical Warfare Agents.”

These and other advancements in toxicology—including nanotoxicology; neurotoxicology; and regulatory science, risk assessment, and decision-making—are all available in the newest issue of the Society’s official journal.