Hyaluronan | sciencenewsnet.in

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Composition of Joint Lubricant Potential Culprit Behind Osteoarthritis

April 11, 2023 sarah JonasResearch Results

The exact mechanism of cartilage breakdown in osteoarthritis is unknown, but damage from mechanical stress with insufficient self-repair is believed to be the main culprit. The composition of synovial fluid, or joint lubricant, changes significantly: The concentration and molecular weight of hyaluronic acid tends to decrease. In Biointerphases, researchers explore the disease-driven breakdown of hyaluronan and the mechanistic implications of these changes on the lubrication and subsequent wear of joints.

NIH study shows hyaluronan is effective in treating chronic lung disease

February 1, 2021 sarah JonasResearch Results

NIH researchers and their collaborators found that inhaling unfragmented hyaluronan improves lung function in patients suffering from severe exacerbation of COPD. Hyaluronan is a sugar secreted by living tissue that acts as a scaffold for cells. Utilized as a treatment, hyaluronan decreased the number of days in the hospital.