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UrduABSTRACTLineage restriction, the biological phenomenon whereby developing cells progressively lose fate potency for all but their adopted lineages, is foundational to multicellular lifeforms as it secures the functional identities of the myriad cell types in the body. The mechanisms of…
Tag: Differentiation
Effects of different concentrations of nicotinamide on hematopoietic stem cells cultured in vitro
BACKGROUNDIn vitro expansion to increase numbers of hematopoietic stem cells (HSCs) in cord blood could improve clinical efficacy of this vital resource. Nicotinamide (NAM) can promote HSC expansion ex vivo, but its effect on hematopoietic
First Stem Cells From a Bat Species Known to Harbor SARS-CoV-2 Could Shed Light on Virus Survival and Molecular Adaptability
Researchers from the Icahn School of Medicine at Mount Sinai have generated the first induced pluripotent stem cells (iPSCs) from bats, gaining valuable insights into the close relationship between bats and viruses.