Modification of Common Diabetes Drug Improved Blood Sugar Control in Mouse Model

Article title: Reduced incretin receptor trafficking upon activation enhances glycemic control and reverses obesity in diet-induced obese mice

Authors: Rathin Bauri, Shilpak Bele, Jhansi Edelli, Neelesh C. Reddy, Sreenivasulu Kurukuti, Tom Devasia, Ahamed Ibrahim, Vishal Rai, Prasenjit Mitra

From the authors: “Chronic administration of I-M-150847 improved glycemic control, enhanced insulin sensitivity, and provided profound weight loss in diet-induced obese mice.”

This study is highlighted as one of July’s “best of the best” as part of the American Physiological Society’s APSselect program.