Researchers take a closer look at both the potential benefits and risks of acetaminophen, NSAIDs such as ibuprofen, as well as aspirin for the selection of OTC drugs to treat mild symptoms of COVID-19.
Tag: non-steroidal anti-inflammatory drugs
CHOP Researchers Reveal How NSAIDs Worsen C. difficile Infections
Why do nonsteroidal anti-inflammatory drugs (NSAIDs) exacerbate gastrointestinal infections by Clostridioides difficile, the leading cause of antibiotic-associated diarrhea worldwide? In a new paper published in Science Advances, researchers at Children’s Hospital of Philadelphia (CHOP) have begun to answer that question, showing that NSAIDs disrupt the mitochondria of cells lining the colon, sensitizing them to damage by pathogenic toxins.