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UrduUnlike central nervous system injuries, peripheral nerve injuries (PNIs) are often characterized by more or less successful axonal regeneration. However, structural and functional recovery is a senile process involving multifaceted cellular
Tag: Mesenchymal
Change in MYCN-driven cell state opens therapeutic window in high-risk neuroblastoma
Scientists at St. Jude Children’s Research Hospital showed that the MYCN protein promotes a switch in the cellular state within the tumor microenvironment, with slow-growing mesenchymal cells swapping to the more dangerous and faster-growing adrenergic state.