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Reversal of Heart Enlargement Differs in the Sexes; Doesn’t Use Universal Signaling Pathways

May 4, 2022 sarah JonasResearch Alert

Article title: Regression from pathological hypertrophy in mice is sexually dimorphic and stimulus-specific Authors: Deanna L. Muehleman, Claudia Crocini, Alison R. Swearingen, Christopher D. Ozeroff, Leslie A. Leinwand From the authors: “This work highlights that the reversal of pathological hypertrophy…

Lack of DUSP5 Protein Leads to Pulmonary Hypertension and Heart Enlargement in Mice

August 3, 2021 sarah JonasResearch Alert

Article title: DUSP5-mediated inhibition of smooth muscle cell proliferation suppresses pulmonary hypertension and right ventricular hypertrophy Authors: Bradley S. Ferguson, Sara A. Wennersten, Kimberly M. Demos-Davies, Marcello Rubino, Emma L. Robinson, Maria A. Cavasin, Matthew S. Stratton, Andrew M. Kidger, Tianjing…