Structure of ‘Oil-Eating’ Enzyme Opens Door to Bioengineered Catalysts

Scientists at Brookhaven National Laboratory have produced the first atomic-level structure of an enzyme that selectively cuts carbon-hydrogen bonds—the first and most challenging step in turning simple hydrocarbons into more useful chemicals. The detailed atomic level “blueprint” suggests ways to engineer the enzyme to produce desired products.

Evolutionary ‘time travel’ reveals enzyme’s origins, possible future designs

“The distinction between the past, present and future is only a stubbornly persistent illusion,” Albert Einstein wrote. Now, researchers have used evolutionary “time travel” to study how an enzyme has evolved, with implications for future design. They will present their results at ACS Fall 2021.