Genomic Surveillance Crucial to Mitigate and Contain COVID-19

Researchers say that genomic surveillance to mitigate and contain COVID-19 is equally crucial to detect variants that are phenotypically or antigenically different well before they spread throughout the U.S. and the rest of the world. Genomic surveillance leverages applications of next-generation sequencing and phylogenetic methods to facilitate greater early anticipation as well as initiation of effective strategies to mitigate and contain outbreaks of SARS-CoV-2 variants and other novel viruses.

Random Effects Key to Containing Epidemics

To control an epidemic, authorities will often impose varying degrees of lockdown. In the journal Chaos, scientists have discovered, using mathematics and computer simulations, why dividing a large population into multiple subpopulations that do not intermix can help contain outbreaks without imposing contact restrictions within those local communities. When infection numbers are high, random effects can be ignored. But subdividing a population can create communities so small that the random effects matter.