Allopregnanolone | sciencenewsnet.in

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Neurosteroid Deficits Leads to Depressed Behavior

February 13, 2023 sarah JonasResearch Results

A study in mice, led by Tufts University School of Medicine scientists, found chronic stress reduced an animal’s abilities to produce and respond to neurosteroids, specifically allopregnanolone.

Neuroactive Steroids May Induce Prolonged Antidepressant Effects by Altering Brain States

August 18, 2021 sarah JonasResearch Results

A new study by researchers from Tufts University School of Medicine and Sage Therapeutics discovered that neurosteroids (allopregnanolone analogs) may alter network states in brain regions involved in emotional processing, which may explain the prolonged antidepressant effects of these compounds.