Implications
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Due to lifestyle similarities and sustained intimate social interaction, humans and animals experience many of the same multifactorial diseases that are influenced by the gut microbiota.
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Physiological interactions with microbial metabolites extend across the entire body to impact virtually every aspect of animal health.
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The microbiome and metabolome can serve as biomarkers of disease risk and progression, as well as a therapeutic target for managing and treating these diseases.
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Consumption of specific dietary ingredients and supplements, especially fiber, elicits microbial production of health-promoting bioactive molecules.