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“Early diagnosis of epilepsy is of the utmost importance because epileptic seizures can lead to injury and even death,” said study author Jacqueline French, MD, of NYU Grossman School of Medicine in New York City and a Fellow of the American Academy of Neurology. “Medications can reduce these risks, but our study found that a history of nonmotor seizures was being missed when children and teens were seen in emergency care.”
Subtle, nonmotor seizures have no noticeable movement. Symptoms affect the senses and may include nausea, visual distortions, feelings of déjà vu, or smelling odd odors. Motor seizures involve uncontrolled movements of the arms and legs and include more severe tonic-clonic seizures with full body convulsions.
The study involved 83 children and teens 12 to 18 years old. All were within four months of starting treatment for focal epilepsy, which accounts for more than half of all epilepsy cases and involves recurring seizures that begin in a localized area of the brain. Researchers reviewed participants’ medical records. There were 39 participants whose first seizure was a motor seizure, and 44 whose first seizure was a nonmotor seizure.
Before diagnosis, 58 went to emergency care for seizures. Looking back at medical records, researchers determined for 32, their first seizure was a motor seizure, and for 26, a nonmotor seizure. But when seeking this emergency care, 90% were seen for motor seizures, with 38% of that group having an unidentified history of nonmotor seizures.
There were 17 participants who were seen for their first motor seizure who had a history of nonmotor seizures, but none were recognized at the time as having had prior nonmotor seizures. As a result, they received similar treatment as those experiencing their first seizure, even though they were more advanced in the disease. French noted nonmotor seizures often worsen over time and progress to tonic-clonic seizures when left untreated.
Researchers found those with initial nonmotor seizures were less likely to seek emergency care with only 59% seeking care compared to 82% of those with initial motor seizures.
In emergency care, researchers also found just 33% of nonmotor seizures were correctly identified compared to 81% of motor seizures.
“Participants with nonmotor seizures described symptoms of hearing repeated phrases or jumbled noises, zoning out and episodes of dizziness, yet for many, this history was not collected until they had a tonic-clonic seizure and were referred to a neurologist,” said French. “This highlights a critical need for doctors to ask about these symptoms when someone seeks care for a motor seizure to ensure they get the best care.”
A limitation of the study was that nonmotor seizures may have been underreported, particularly in children who may have had difficulty identifying and communicating the symptoms of those seizures.
Learn more about epilepsy at BrainandLife.org, home of the American Academy of Neurology’s free patient and caregiver magazine focused on the intersection of neurologic disease and brain health. Follow Brain & Life® on Facebook, X and Instagram.
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The American Academy of Neurology is the world’s largest association of neurologists and neuroscience professionals, with over 40,000 members. The AAN’s mission is to enhance member career fulfillment and promote brain health for all. A neurologist is a doctor with specialized training in diagnosing, treating and managing disorders of the brain and nervous system such as Alzheimer’s disease, stroke, concussion, epilepsy, Parkinson’s disease, multiple sclerosis, headache and migraine.
For more information about the American Academy of Neurology, visit AAN.com or find us on Facebook, X, Instagram, LinkedIn and YouTube
