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Sotorasib shows clinically meaningful activity in KRAS G12C-mutated advanced pancreatic cancer

December 21, 2022 sarah JonasResearch Results

In the Phase I/II CodeBreaK 100 trial, the KRAS G12C inhibitor sotorasib achieved meaningful anticancer activity with an acceptable safety profile in heavily pretreated patients with KRAS G12C-mutated metastatic pancreatic cancer, according to researchers at The University of Texas MD Anderson Cancer Center.