The organisms that cause visceral leishmaniasis, a potentially deadly version of the parasitic disease that most often affects the skin, appear to have a secret weapon, new research suggests: They can infect non-immune cells and persist in those uncommon environments.
Tag: Single-cell RNA Sequencing
HER2 Pathways in Breast Cancer May Hold Key to Effective Treatment of Idiopathic Pulmonary Fibrosis
LOS ANGELES (Oct. 13, 2022) — FINDINGS A new study led by Cedars-Sinai investigators suggests HER2 signaling may be a key driver of fibroblast invasion and can serve as a target for therapeutic intervention in idiopathic pulmonary fibrosis. HER2 is…
Single-cell analysis of metastatic gastric cancer finds diverse tumor cell populations associated with patient outcomes
Researchers from The University of Texas MD Anderson Cancer Center who profiled more than 45,000 individual cells from patients with peritoneal carcinomatosis (PC), a specific form of metastatic gastric cancer, defined the extensive cellular heterogeneity and identified two distinct subtypes correlated with patient survival.