In a study with mice reported today in the journal Science Translational Medicine, a Johns Hopkins Medicine research team has provided what may be the most definitive view to date of the biological process leading to necrotizing enterocolitis (NEC), a dangerous inflammatory disease that can destroy a premature infant’s intestinal lining and causes death in up to a third of the cases.
Tag: Preemies
Betamethasome before Delivery May Preserve Right Ventricular Heart Function in Preemies
Article title: Antenatal betamethasone redistributes central blood flows and preferentially augments right ventricular output and pump function in preterm fetal lambs Authors: Joseph J. Smolich and Jonathan P. Mynard From the authors: “These findings suggest that antenatal betamethasone produces a widespread…
Placental Stem Cells Show Promise for Treating Preemies’ Necrotizing Enterocolitis
Article title: Human placental-derived stem cell therapy ameliorates experimental necrotizing enterocolitis Authors: Victoria G. Weis, Anna C. Deal, Gehad Mekky, Cara Clouse, Michaela Gaffley, Emily Whitaker, Cole B. Peeler, Jared A. Weis, Marshall Z. Schwartz, Anthony Atala From the authors:…
Airway Smooth Muscle Clock May Be a Target for Treating Preemies
Article title: Cellular clocks in hyperoxia effects on [Ca2+]i regulation in developing human airway smooth muscle Authors: Colleen M. Bartman, Aleksey Matveyenko, Christina M. Pabelick, Y. S. Prakash From the authors: “These data reveal a functional [fetal airway smooth muscle] clock…